Endocrine Abstracts

Testing for genetic markers is a promising approach in early diagnosis of type 1 diabetes mellitus (DM1). Of all DM1-associated genes and genetic loci, after HLA class II, insulin promoter gene confers the highest risk for the onset of disease with the burdened familial history for diabetes mellitus.Materials and methodsGenealogical analysis was used to identify the hereditary nature of the disease. DNA samples from 94 Uzbek patien...